Interaction of the Cytosolic Domains of sorLA/LR11 with the Amyloid Precursor Protein (APP) and β-Secretase β-Site APP-Cleaving Enzyme

sorLA is a recently identified neuronal receptor for amyloid precursor protein (APP) that is known to interact with APP and affect its intracellular transport and processing. Decreased levels of sorLA in the brain of Alzheimer's disease (AD) patients and elevated levels of amyloid-β peptide (Aβ...

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Udgivet i:J Neurosci
Main Authors: Spoelgen, Robert, von Arnim, Christine A. F., Thomas, Anne V., Peltan, Ithan D., Koker, Mirjam, Deng, Amy, Irizarry, Michael C., Andersen, Olav M., Willnow, Thomas E., Hyman, Bradley T.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Neurobiology of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674411/
https://ncbi.nlm.nih.gov/pubmed/16407538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3882-05.2006
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