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Neuronal LR11/SorLA Expression Is Reduced in Mild Cognitive Impairment
OBJECTIVE: LR11 (aka sorLA) is a multifunctional neuronal receptor that binds apolipoprotein E and interacts with amyloid precursor protein to regulate amyloidogenesis. Reduced expression of LR11, as occurs in the brains of individuals with Alzheimer’s disease (AD), increases amyloidogenesis, and va...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669325/ https://ncbi.nlm.nih.gov/pubmed/17721864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21190 |
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