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LR11/SorLA Expression Is Reduced in Sporadic Alzheimer Disease but not in Familial Alzheimer Disease

LR11 is an ApoE receptor that is enriched in the brain. We have shown that LR11 is markedly downregulated in patients with sporadic Alzheimer disease (AD). This finding led us to explore whether reduced LR11 expression reflects a primary mechanism of disease or merely a secondary consequence of othe...

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Détails bibliographiques
Auteurs principaux: Dodson, Sara E., Gearing, Marla, Lippa, Carol F., Montine, Thomas J., Levey, Allan I., Lah, James J.
Format: Artigo
Langue:Inglês
Publié: 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663339/
https://ncbi.nlm.nih.gov/pubmed/16957580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.jnen.0000228205.19915.20
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