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LR11/SorLA Expression Is Reduced in Sporadic Alzheimer Disease but not in Familial Alzheimer Disease

LR11 is an ApoE receptor that is enriched in the brain. We have shown that LR11 is markedly downregulated in patients with sporadic Alzheimer disease (AD). This finding led us to explore whether reduced LR11 expression reflects a primary mechanism of disease or merely a secondary consequence of othe...

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Bibliografiska uppgifter
Huvudupphovsmän: Dodson, Sara E., Gearing, Marla, Lippa, Carol F., Montine, Thomas J., Levey, Allan I., Lah, James J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663339/
https://ncbi.nlm.nih.gov/pubmed/16957580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.jnen.0000228205.19915.20
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