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The Lipoprotein Receptor LR11 Regulates Amyloid β Production and Amyloid Precursor Protein Traffic in Endosomal Compartments

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and neuropathological changes, including the deposition of amyloid β (Aβ) in senile plaques. The mechanisms causing the disease and Aβ accumulation are not well understood, but important genetic a...

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Autors principals: Offe, Katrin, Dodson, Sara E., Shoemaker, James T., Fritz, Jason J., Gearing, Marla, Levey, Allan I., Lah, James J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638122/
https://ncbi.nlm.nih.gov/pubmed/16452683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4946-05.2006
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