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Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro
BACKGROUND AND PURPOSE: There is significant variation in individual response to opioid drugs, which may result in inappropriate opioid therapy. Polymorphisms of the μ opioid receptor (MOP receptor) may contribute to individual variation in opioid response by affecting receptor function, and the eff...
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| Pubblicato in: | Br J Pharmacol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241093/ https://ncbi.nlm.nih.gov/pubmed/24846673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12785 |
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