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Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro

BACKGROUND AND PURPOSE: There is significant variation in individual response to opioid drugs, which may result in inappropriate opioid therapy. Polymorphisms of the μ opioid receptor (MOP receptor) may contribute to individual variation in opioid response by affecting receptor function, and the eff...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Knapman, Alisa, Santiago, Marina, Connor, Mark
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241093/
https://ncbi.nlm.nih.gov/pubmed/24846673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12785
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