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A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro
BACKGROUND AND PURPOSE: Polymorphisms of the μ opioid receptor (MOPr) may contribute to the variation in responses to opioid drugs in clinical and unregulated situations. The A6V variant of MOPr (MOPr-A6V) is present in up to 20% of individuals in some populations, and may be associated with heighte...
Sparad:
| I publikationen: | Br J Pharmacol |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BlackWell Publishing Ltd
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403092/ https://ncbi.nlm.nih.gov/pubmed/25521224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13047 |
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