Buprenorphine-Induced Antinociception Is Mediated by μ-Opioid Receptors and Compromised by Concomitant Activation of Opioid Receptor-Like Receptors

Buprenorphine is a mixed opioid receptor agonist-antagonist used clinically for maintenance therapy in opiate addicts and pain management. Dose-response curves for buprenorphine-induced antinociception display ceiling effects or are bell shaped, which have been attributed to the partial agonist acti...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Lutfy, Kabirullah, Eitan, Shoshana, Bryant, Camron D., Yang, Yu C., Saliminejad, Nazli, Walwyn, Wendy, Kieffer, Brigitte L., Takeshima, Hiroshi, Carroll, F. Ivy, Maidment, Nigel T., Evans, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Behavioral/Systems/Cognitive
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741014/
https://ncbi.nlm.nih.gov/pubmed/14614092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-32-10331.2003
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