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Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.
We have characterized the determinants of methotrexate (MTX) responsiveness in eight patient-derived cell lines of small-cell lung cancer (SCLC). Clonogenic survival was correlated with factors known to affect sensitivity to drug. NCI-H209 and NCI-H128 were most drug sensitive, with drug concentrati...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2414316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112106 |
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