Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.

We have characterized the determinants of methotrexate (MTX) responsiveness in eight patient-derived cell lines of small-cell lung cancer (SCLC). Clonogenic survival was correlated with factors known to affect sensitivity to drug. NCI-H209 and NCI-H128 were most drug sensitive, with drug concentrati...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Invest
Main Authors: Curt, G A, Jolivet, J, Carney, D N, Bailey, B D, Drake, J C, Clendeninn, N J, Chabner, B A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2414316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112106
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items