The putative signal peptide of glucagon-like peptide-1 receptor is not required for receptor synthesis but promotes receptor expression

GLP-1R (glucagon-like peptide-1 receptor) mediates the ‘incretin effect’ and many other anti-diabetic actions of its cognate ligand, GLP-1 (glucagon-like peptide-1). It belongs to the class B family of GPCRs (G protein-coupled receptors) and possesses an N-terminal putative SP (signal peptide). It h...

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Ge, Yunjun, Yang, Dehua, Dai, Antao, Zhou, Caihong, Zhu, Yue, Wang, Ming-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2014
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240022/
https://ncbi.nlm.nih.gov/pubmed/25330813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140120
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