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Role of the signal peptide in the synthesis and processing of the glucagon-like peptide-1 receptor

BACKGROUND AND PURPOSE: The glucagon-like peptide-1 receptor (GLP-1R) belongs to Family B of the G protein-coupled receptor superfamily and is a target for treatment of type 2 diabetes. Family B G protein-coupled receptors contain a putative N-terminal signal peptide, but its role in receptor synthe...

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Detalhes bibliográficos
Main Authors: Huang, Y, Wilkinson, GF, Willars, GB
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823368/
https://ncbi.nlm.nih.gov/pubmed/20002095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00517.x
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