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Synthesis and biological evaluation of glucagon-like peptide-1 receptor agonists

In this study, a series of fused-heterocyclic derivatives were systematically designed and synthesized using an efficient route, and evaluated in terms of GLP-1R agonist activity. We employed short synthetic steps and reactions that are tolerant of the presence of various functional groups and suita...

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Detalles Bibliográficos
Main Authors: Zhang, Yu-Juan, Shen, Liu-Lan, Cheon, Hyae-Gyeong, Xu, Yong-Nan, Jeong, Jin-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Pharmaceutical Society of Korea 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016675/
https://ncbi.nlm.nih.gov/pubmed/24178744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12272-013-0253-9
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