Small-molecule agonists for the glucagon-like peptide 1 receptor

The peptide hormone glucagon-like peptide (GLP)-1 has important actions resulting in glucose lowering along with weight loss in patients with type 2 diabetes. As a peptide hormone, GLP-1 has to be administered by injection. Only a few small-molecule agonists to peptide hormone receptors have been de...

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Main Authors: Knudsen, Lotte Bjerre, Kiel, Dan, Teng, Min, Behrens, Carsten, Bhumralkar, Dilip, Kodra, János T., Holst, Jens J., Jeppesen, Claus B., Johnson, Michael D., de Jong, Johannes Cornelis, Jorgensen, Anker Steen, Kercher, Tim, Kostrowicki, Jarek, Madsen, Peter, Olesen, Preben H., Petersen, Jacob S., Poulsen, Fritz, Sidelmann, Ulla G., Sturis, Jeppe, Truesdale, Larry, May, John, Lau, Jesper
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783418/
https://ncbi.nlm.nih.gov/pubmed/17213325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605701104
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