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Small-molecule agonists for the glucagon-like peptide 1 receptor

The peptide hormone glucagon-like peptide (GLP)-1 has important actions resulting in glucose lowering along with weight loss in patients with type 2 diabetes. As a peptide hormone, GLP-1 has to be administered by injection. Only a few small-molecule agonists to peptide hormone receptors have been de...

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Hlavní autoři: Knudsen, Lotte Bjerre, Kiel, Dan, Teng, Min, Behrens, Carsten, Bhumralkar, Dilip, Kodra, János T., Holst, Jens J., Jeppesen, Claus B., Johnson, Michael D., de Jong, Johannes Cornelis, Jorgensen, Anker Steen, Kercher, Tim, Kostrowicki, Jarek, Madsen, Peter, Olesen, Preben H., Petersen, Jacob S., Poulsen, Fritz, Sidelmann, Ulla G., Sturis, Jeppe, Truesdale, Larry, May, John, Lau, Jesper
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783418/
https://ncbi.nlm.nih.gov/pubmed/17213325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605701104
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