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Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes

BACKGROUND: The evolution of a cancer genome has traditionally been described as a sequential accumulation of mutations - including chromosomal rearrangements - over a period of time. Recent research suggests, however, that numerous rearrangements may be acquired simultaneously during a single catac...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Weinreb, Caleb, Oesper, Layla, Raphael, Benjamin J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239675/
https://ncbi.nlm.nih.gov/pubmed/25572114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S6-S4
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