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AMPylation of Rho GTPases Subverts Multiple Host Signaling Processes

Rho GTPases are frequent targets of virulence factors as they are keystone signaling molecules. Herein, we demonstrate that AMPylation of Rho GTPases by VopS is a multifaceted virulence mechanism that counters several host immunity strategies. Activation of NFκB, Erk, and JNK kinase signaling pathwa...

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Vydáno v:J Biol Chem
Hlavní autoři: Woolery, Andrew R., Yu, Xiaobo, LaBaer, Joshua, Orth, Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239643/
https://ncbi.nlm.nih.gov/pubmed/25301945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601310
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