Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDIα) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion

Conventional protein kinase C (PKC) isoforms are essential serine/threonine kinases regulating many signaling networks. At cell adhesion sites, PKCα can impact the actin cytoskeleton through its influence on RhoGTPases, but the intermediate steps are not well known. One important regulator of RhoGTP...

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Detalhes bibliográficos
Main Authors: Dovas, Athanassios, Choi, Youngsil, Yoneda, Atsuko, Multhaupt, Hinke A. B., Kwon, Seung-Hae, Kang, Dongmin, Oh, Eok-Soo, Couchman, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906322/
https://ncbi.nlm.nih.gov/pubmed/20472934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098129
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