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RhoGDI2 suppresses metastasis via unconventional regulation of RhoGTPases

RhoGDI2 has been identified as a metastasis suppressor in bladder and possibly other cancers (1). This protein is a member of a family of proteins that maintain Rho GTPases in the cytoplasm and inhibit their activation and function. To understand the mechanism of metastasis suppression, we compared...

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Autori principali: Moissoglu, Konstadinos, McRoberts, Kevin S., Meier, Jeremy A., Theodorescu, Dan, Schwartz, Martin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701105/
https://ncbi.nlm.nih.gov/pubmed/19276387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1397
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