Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDIα) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion

Conventional protein kinase C (PKC) isoforms are essential serine/threonine kinases regulating many signaling networks. At cell adhesion sites, PKCα can impact the actin cytoskeleton through its influence on RhoGTPases, but the intermediate steps are not well known. One important regulator of RhoGTP...

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Autores principales: Dovas, Athanassios, Choi, Youngsil, Yoneda, Atsuko, Multhaupt, Hinke A. B., Kwon, Seung-Hae, Kang, Dongmin, Oh, Eok-Soo, Couchman, John R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906322/
https://ncbi.nlm.nih.gov/pubmed/20472934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098129
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