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AMPylation of Rho GTPases Subverts Multiple Host Signaling Processes
Rho GTPases are frequent targets of virulence factors as they are keystone signaling molecules. Herein, we demonstrate that AMPylation of Rho GTPases by VopS is a multifaceted virulence mechanism that counters several host immunity strategies. Activation of NFκB, Erk, and JNK kinase signaling pathwa...
Guardat en:
| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239643/ https://ncbi.nlm.nih.gov/pubmed/25301945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601310 |
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