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AMPylation of Rho GTPases Subverts Multiple Host Signaling Processes

Rho GTPases are frequent targets of virulence factors as they are keystone signaling molecules. Herein, we demonstrate that AMPylation of Rho GTPases by VopS is a multifaceted virulence mechanism that counters several host immunity strategies. Activation of NFκB, Erk, and JNK kinase signaling pathwa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Woolery, Andrew R., Yu, Xiaobo, LaBaer, Joshua, Orth, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239643/
https://ncbi.nlm.nih.gov/pubmed/25301945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601310
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