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Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates
The human cytochrome P450 17A1 (CYP17A1) enzyme operates at a key juncture of human steroidogenesis, controlling the levels of mineralocorticoids influencing blood pressure, glucocorticoids involved in immune and stress responses, and androgens and estrogens involved in development and homeostasis o...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239641/ https://ncbi.nlm.nih.gov/pubmed/25301938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610998 |
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