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Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates

The human cytochrome P450 17A1 (CYP17A1) enzyme operates at a key juncture of human steroidogenesis, controlling the levels of mineralocorticoids influencing blood pressure, glucocorticoids involved in immune and stress responses, and androgens and estrogens involved in development and homeostasis o...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Petrunak, Elyse M., DeVore, Natasha M., Porubsky, Patrick R., Scott, Emily E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239641/
https://ncbi.nlm.nih.gov/pubmed/25301938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610998
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