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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model
Clonal proliferation of plasma cells within the bone marrow (BM) affects local cells, such as mesenchymal stromal cells (MSCs), leading to osteolysis and fatality in multiple myeloma (MM). Consequently, there is an urgent need to find better mechanisms of inhibiting myeloma growth and osteolytic les...
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| Veröffentlicht in: | Blood |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239334/ https://ncbi.nlm.nih.gov/pubmed/25205118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-558007 |
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