CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation

Extra-medullary disease (EMD) in Multiple Myeloma (MM) is associated with poor prognosis and resistance to chemotherapy. However, molecular alterations that lead to EMD have not been well defined. We developed bone marrow (BM)- and EMD-prone MM syngeneic cell lines and identified that epithelial-to-...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Rep
Κύριοι συγγραφείς: Roccaro, Aldo M., Mishima, Yuji, Sacco, Antonio, Moschetta, Michele, Tai, Yu-Tzu, Shi, Jiantao, Zhang, Yong, Reagan, Michaela R., Huynh, Daisy, Kawano, Yawara, Sahin, Ilyas, Chiarini, Marco, Manier, Salomon, Cea, Michele, Aljawai, Yosra, Glavey, Siobhan, Morgan, Elizabeth, Pan, Chin, Michor, Franziska, Cardarelli, Pina, Kuhne, Michelle, Ghobrial, Irene M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2015
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961259/
https://ncbi.nlm.nih.gov/pubmed/26190113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.059
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