Global Epigenetic Regulation of MicroRNAs in Multiple Myeloma

Epigenetic changes frequently occur during tumorigenesis and DNA hypermethylation may account for the inactivation of tumor suppressor genes in cancer cells. Studies in Multiple Myeloma (MM) have shown variable DNA methylation patterns with focal hypermethylation changes in clinically aggressive sub...

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Hauptverfasser: Zhang, Wenjing, Wang, Yaoyu E., Zhang, Yu, Leleu, Xavier, Reagan, Michaela, Zhang, Yong, Mishima, Yuji, Glavey, Siobhan, Manier, Salomon, Sacco, Antonio, Jiang, Bo, Roccaro, Aldo M., Ghobrial, Irene M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201574/
https://ncbi.nlm.nih.gov/pubmed/25330074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110973
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