Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

Clonal proliferation of plasma cells within the bone marrow (BM) affects local cells, such as mesenchymal stromal cells (MSCs), leading to osteolysis and fatality in multiple myeloma (MM). Consequently, there is an urgent need to find better mechanisms of inhibiting myeloma growth and osteolytic les...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2014
Θέματα:
Lymphoid Neoplasia
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239334/
https://ncbi.nlm.nih.gov/pubmed/25205118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-558007
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