טוען...
Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells
The efficacy of most therapeutic monoclonal antibodies (mAbs) targeting tumor antigens results primarily from their ability to elicit potent cytotoxicity through effector-mediated functions. We have engineered the fragment crystallizable (Fc) region of the immunoglobulin G (IgG) mAb, HuM195, targeti...
שמור ב:
| הוצא לאור ב: | Blood |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239333/ https://ncbi.nlm.nih.gov/pubmed/25232058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-569061 |
| תגים: |
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