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Individual motile CD4(+) T cells can participate in efficient multi-killing through conjugation to multiple tumor cells

T cells genetically modified to express a CD19-specific chimeric antigen receptor (CAR) for the investigational treatment of B-cell malignancies comprise a heterogeneous population, and their ability to persist and participate in serial killing of tumor cells is a predictor of therapeutic success. W...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Immunol Res
मुख्य लेखकों: Liadi, Ivan, Singh, Harjeet, Romain, Gabrielle, Rey-Villamizar, Nicolas, Merouane, Amine, Adolacion, Jay R T., Kebriaei, Partow, Huls, Helen, Qiu, Peng, Roysam, Badrinath, Cooper, Laurence J.N., Varadarajan, Navin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421910/
https://ncbi.nlm.nih.gov/pubmed/25711538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0195
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