T-bet:Eomes Balance, Effector Function and Proliferation of CMV-specific CD8(+) T-cells during Primary Infection Differentiates the Capacity for Durable Immune Control

CMV remains an important opportunistic pathogen in solid organ transplantation, particularly in lung transplant recipients (LTRs). LTRs mismatched for CMV (donor+/recipient−; D+R−) are at high-risk for active CMV infection and increased mortality, however the immune correlates of viral control remai...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Popescu, Iulia, Pipeling, Matthew R., Shah, Pali D., Orens, Jonathan B., McDyer, John F.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239205/
https://ncbi.nlm.nih.gov/pubmed/25339676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401436
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