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Early KLRG1(+) but not CD57(+)CD8(+) T cells in Primary CMV Infection Predict Effector Function and Viral Control

CMV remains an important opportunistic pathogen in high-risk lung transplant recipients (LTRs). We characterized the phenotype and function of CD8(+) T cells from acute/primary into chronic CMV infection in 23 (donor+/recipient-; D+R-) LTRs and found rapid induction of both KLRG1(+) and/or CD57(+) C...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Hoji, Aki, Popescu, Iulia D., Pipeling, Mathew R., Shah, Pali D., Winters, Spencer A., McDyer, John F.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081945/
https://ncbi.nlm.nih.gov/pubmed/31554693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900399
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