Reduced Ebola vaccine responses in CMV(+) young adults is associated with expansion of CD57(+)KLRG1(+) T cells

CMV is associated with immunosenescence and reduced vaccine responses in the elderly (>70 yr). However, the impact of CMV in young adults is less clear. In this study, healthy UK and Senegalese adults aged 18–50 yr (average, 29 yr) were vaccinated with the Ebola vaccine candidate chimpanzee adeno...

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Библиографические подробности
Опубликовано в: :J Exp Med
Главные авторы: Bowyer, Georgina, Sharpe, Hannah, Venkatraman, Navin, Ndiaye, Pierre Birahim, Wade, Djibril, Brenner, Nicole, Mentzer, Alex, Mair, Catherine, Waterboer, Tim, Lambe, Teresa, Dieye, Tandakha, Mboup, Souleymane, Hill, Adrian V.S., Ewer, Katie J.
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2020
Предметы:
Brief Definitive Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336307/
https://ncbi.nlm.nih.gov/pubmed/32413101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200004
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