Reduced Ebola vaccine responses in CMV(+) young adults is associated with expansion of CD57(+)KLRG1(+) T cells

CMV is associated with immunosenescence and reduced vaccine responses in the elderly (>70 yr). However, the impact of CMV in young adults is less clear. In this study, healthy UK and Senegalese adults aged 18–50 yr (average, 29 yr) were vaccinated with the Ebola vaccine candidate chimpanzee adeno...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Bowyer, Georgina, Sharpe, Hannah, Venkatraman, Navin, Ndiaye, Pierre Birahim, Wade, Djibril, Brenner, Nicole, Mentzer, Alex, Mair, Catherine, Waterboer, Tim, Lambe, Teresa, Dieye, Tandakha, Mboup, Souleymane, Hill, Adrian V.S., Ewer, Katie J.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336307/
https://ncbi.nlm.nih.gov/pubmed/32413101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200004
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