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Interleukin 12-dependent Cytomegalovirus-Specific CD4(+) T cell Proliferation, T-bet induction and Effector Multi-function during Primary Infection are Key Determinants for Early Immune Control
CMV remains an important opportunistic pathogen in solid organ and hematopoietic cell transplantation, particularly in lung transplant recipients (LTRs). LTRs mismatched for CMV (donor+/recipient−; D+R−) are at high-risk for active CMV infection and increased mortality; however the immune correlates...
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出版年: | J Immunol |
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主要な著者: | , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707074/ https://ncbi.nlm.nih.gov/pubmed/26663780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501589 |
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