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T-bet:Eomes Balance, Effector Function and Proliferation of CMV-specific CD8(+) T-cells during Primary Infection Differentiates the Capacity for Durable Immune Control

CMV remains an important opportunistic pathogen in solid organ transplantation, particularly in lung transplant recipients (LTRs). LTRs mismatched for CMV (donor+/recipient−; D+R−) are at high-risk for active CMV infection and increased mortality, however the immune correlates of viral control remai...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Popescu, Iulia, Pipeling, Matthew R., Shah, Pali D., Orens, Jonathan B., McDyer, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239205/
https://ncbi.nlm.nih.gov/pubmed/25339676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401436
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