Diminished type I collagen synthesis and reduced alpha 1(I) collagen messenger RNA in cultured fibroblasts from patients with dominantly inherited (type I) osteogenesis imperfecta.

Type I osteogenesis imperfecta (OI) is characterized clinically by a moderate fracture frequency with minimal bone deformity and dominant inheritance. Previous studies of the collagenous proteins synthesized by dermal fibroblasts obtained from unrelated patients with this form of OI suggested that t...

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Dades bibliogràfiques
Autors principals: Rowe, D W, Shapiro, J R, Poirier, M, Schlesinger, S
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC423866/
https://ncbi.nlm.nih.gov/pubmed/4031065
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