Diminished type I collagen synthesis and reduced alpha 1(I) collagen messenger RNA in cultured fibroblasts from patients with dominantly inherited (type I) osteogenesis imperfecta.

Type I osteogenesis imperfecta (OI) is characterized clinically by a moderate fracture frequency with minimal bone deformity and dominant inheritance. Previous studies of the collagenous proteins synthesized by dermal fibroblasts obtained from unrelated patients with this form of OI suggested that t...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Rowe, D W, Shapiro, J R, Poirier, M, Schlesinger, S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4031065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112012
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