In Vivo Evaluation of Adeno-Associated Virus Gene Transfer in Airways of Mice with Acute or Chronic Respiratory Infection

Patients with cystic fibrosis (CF) often suffer chronic lung infection with concomitant inflammation, a setting that may reduce the efficacy of gene transfer. While gene therapy development for CF often involves viral-based vectors, little is known about gene transfer in the context of an infected a...

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Bibliografiske detaljer
Udgivet i:Hum Gene Ther
Main Authors: Myint, Melissa, Limberis, Maria P., Bell, Peter, Somanathan, Suryanarayan, Haczku, Angela, Wilson, James M., Diamond, Scott L.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235593/
https://ncbi.nlm.nih.gov/pubmed/25144316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.002
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