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BALB/c Mice Show Impaired Hepatic Tolerogenic Response Following AAV Gene Transfer to the Liver

Following adeno-associated virus (AAV) gene transfer to the liver, both C57BL/6 and BALB/c mice show long-term expression of nonself transgene antigens along with the absence of a transgene-specific immune response. However, in this study, we report that despite the equal ability to induce T-cell to...

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Detalhes bibliográficos
Main Authors: Breous, Ekaterina, Somanathan, Suryanarayan, Wilson, James M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862531/
https://ncbi.nlm.nih.gov/pubmed/20068550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.301
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