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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver

The mechanisms of tolerance in the liver that limit susceptibility to food allergy and that mediate the acceptance of liver transplants even with a complete MHC mismatch remain poorly defined. Here we report that in a model of liver-directed gene transfer cytotoxic T lymphocyte (CTL) responses to no...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Breous, Ekaterina, Somanathan, Suryanarayan, Vandenberghe, Luk H., Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380144/
https://ncbi.nlm.nih.gov/pubmed/19575456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23043
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