Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity

[Image: see text] Through a “tag-and-modify” protein chemical modification strategy, we site-selectively phosphorylated the activation loop of protein kinase p38α. Phosphorylation at natural (180) and unnatural (172) sites created two pure phospho-forms. p38α bearing only a single phosphocysteine (p...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Chooi, K. Phin, Galan, Sébastien R. G., Raj, Ritu, McCullagh, James, Mohammed, Shabaz, Jones, Lyn H., Davis, Benjamin G.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235370/
https://ncbi.nlm.nih.gov/pubmed/24393126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4095318
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars