LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome

Enzyme-mediated damage repair or mitigation, whilst common for nucleic acids, is rare for proteins. Examples of protein damage are elimination of phosphorylated Ser/Thr to dehydroalanine/dehydrobutyrine (Dha/Dhb) in pathogenesis and aging. Bacterial LanC enzymes use Dha/Dhb to form carbon-sulfur lin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell
मुख्य लेखकों: Lai, Kuan-Yu, Galan, Sébastien R. G., Zeng, Yibo, Zhou, Hina, He, Chang, Raj, Ritu, Riedl, Jitka, Liu, Shi, Chooi, K. Phin, Garg, Neha, Zeng, Min, Jones, Lyn H., Hutchings, Graham J., Mohammed, Shabaz, Nair, Satish K., Chen, Jie, Davis, Benjamin G., van der Donk, Wilfred A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209957/
https://ncbi.nlm.nih.gov/pubmed/33932340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.04.001
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