LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome

Enzyme-mediated damage repair or mitigation, whilst common for nucleic acids, is rare for proteins. Examples of protein damage are elimination of phosphorylated Ser/Thr to dehydroalanine/dehydrobutyrine (Dha/Dhb) in pathogenesis and aging. Bacterial LanC enzymes use Dha/Dhb to form carbon-sulfur lin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Lai, Kuan-Yu, Galan, Sébastien R. G., Zeng, Yibo, Zhou, Hina, He, Chang, Raj, Ritu, Riedl, Jitka, Liu, Shi, Chooi, K. Phin, Garg, Neha, Zeng, Min, Jones, Lyn H., Hutchings, Graham J., Mohammed, Shabaz, Nair, Satish K., Chen, Jie, Davis, Benjamin G., van der Donk, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209957/
https://ncbi.nlm.nih.gov/pubmed/33932340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.04.001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker