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Synthetic Nucleosomes Reveal that GlcNAcylation Modulates Direct Interaction with the FACT Complex

Transcriptional regulation can be established by various post‐translational modifications (PTMs) on histone proteins in the nucleosome and by nucleobase modifications on chromosomal DNA. Functional consequences of histone O‐GlcNAcylation (O‐GlcNAc=O‐linked β‐N‐acetylglucosamine) are largely unexplor...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Raj, Ritu, Lercher, Lukas, Mohammed, Shabaz, Davis, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111754/
https://ncbi.nlm.nih.gov/pubmed/27272618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603106
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