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Synthetic Nucleosomes Reveal that GlcNAcylation Modulates Direct Interaction with the FACT Complex

Transcriptional regulation can be established by various post‐translational modifications (PTMs) on histone proteins in the nucleosome and by nucleobase modifications on chromosomal DNA. Functional consequences of histone O‐GlcNAcylation (O‐GlcNAc=O‐linked β‐N‐acetylglucosamine) are largely unexplor...

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Bibliografske podrobnosti
izdano v:Angew Chem Int Ed Engl
Main Authors: Raj, Ritu, Lercher, Lukas, Mohammed, Shabaz, Davis, Benjamin G.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111754/
https://ncbi.nlm.nih.gov/pubmed/27272618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603106
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