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Allosteric induction of the CD4-bound conformation of HIV-1 Gp120
BACKGROUND: HIV-1 infection of target cells is mediated via the binding of the viral envelope protein, gp120, to the cell surface receptor CD4. This interaction leads to conformational rearrangements in gp120 forming or revealing CD4 induced (CD4i) epitopes which are critical for the subsequent reco...
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| Publicado no: | Retrovirology |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235218/ https://ncbi.nlm.nih.gov/pubmed/24304511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-147 |
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