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Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies

The HIV envelope binds cellular CD4 and undergoes a range of conformational changes that lead to membrane fusion and delivery of the viral nucleocapsid into the cellular cytoplasm. This binding to CD4 reveals cryptic and highly conserved epitopes, the molecular nature of which is still not fully und...

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Pubblicato in:J Virol
Autori principali: Kaplan, Gilad, Roitburd-Berman, Anna, Lewis, George K., Gershoni, Jonathan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836356/
https://ncbi.nlm.nih.gov/pubmed/26889042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03206-15
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