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Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies

The HIV envelope binds cellular CD4 and undergoes a range of conformational changes that lead to membrane fusion and delivery of the viral nucleocapsid into the cellular cytoplasm. This binding to CD4 reveals cryptic and highly conserved epitopes, the molecular nature of which is still not fully und...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kaplan, Gilad, Roitburd-Berman, Anna, Lewis, George K., Gershoni, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836356/
https://ncbi.nlm.nih.gov/pubmed/26889042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03206-15
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