CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization

Human immunodeficiency virus type 1 (HIV-1) entry into target cells involves sequential binding of the gp120 exterior envelope glycoprotein to CD4 and to specific chemokine receptors. Soluble CD4 (sCD4) is thought to mimic membrane-anchored CD4, and its binding alters the conformation of the HIV-1 e...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sullivan, Nancy, Sun, Ying, Sattentau, Quentin, Thali, Markus, Wu, Dona, Denisova, Galina, Gershoni, Jonathan, Robinson, James, Moore, John, Sodroski, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4694-4703.1998
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