The general mode of translation inhibition by macrolide antibiotics

Macrolides are clinically important antibiotics thought to inhibit bacterial growth by impeding the passage of newly synthesized polypeptides through the nascent peptide exit tunnel of the bacterial ribosome. Recent data challenged this view by showing that macrolide antibiotics can differentially a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kannan, Krishna, Kanabar, Pinal, Schryer, David, Florin, Tanja, Oh, Eugene, Bahroos, Neil, Tenson, Tanel, Weissman, Jonathan S., Mankin, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234590/
https://ncbi.nlm.nih.gov/pubmed/25349425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417334111
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